Study summary

In vitro inactivation of porcine reproductive and respiratory syndrome virus and pseudorabies virus by slightly acidic electrolyzed water

The Veterinary Journal · 2013

Summary

Abstract

Slightly acidic electrolyzed water (SAEW, pH 5.0 6.5) is a novel disinfectant with environmentally friendly broad spectrum microbial decontamination properties which could have significant utility on farm. Two of the most important pathogenic viruses in pigs are porcine reproductive and respiratory syndrome virus (PRRSV) and pseudorabies virus (PRV). The aim of this study was to evaluate the viricidal effectiveness of SAEW against PRRSV and PRV in vitro under different available chlorine concentrations (ACCs, 30, 50 and 70 mg/L), treatment times (5, 10 and 15 min) and temperatures (4, 20, 40 and 60 C), respectively. SAEW had a strong viricidal activity against both PRRSV and PRV. This activity increased with increasing ACC, treatment time and temperature. PRRSV and PRV titres of 7.0 log10 TCID50/mL and 5.9 log10 TCID50/mL, respectively, were completely inactivated by SAEW at an ACC of 50 mg/L for 10 min even though SAEW had no negative effect on the host cells. SAEW thus shows promise as a disinfectant for use on pig farms to reduce the spread of both PRRSV and PRV, and to limit the morbidity associated with those viruses.

Study details

  • Published in: The Veterinary Journal 197.2 (2013): 297-301
  • Microbes studied: porcine reproductive virus, respiratory syndrome virus

Source

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Source: The Veterinary Journal 197.2 (2013): 297-301

Conditions tested

ParameterValue
OrganismsViruses (general)
Relevant sectorsLivestock
PublicationThe Veterinary Journal, 2013

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