Summary
Abstract
Electrolyzed products of a sodium chloride solution contain free residual chlorine and have been proved to be effective for disinfection. Electrolyzed strong acid water containing a low sodium chloride concentration (ESW-L) is prepared by the electrolysis of a solution containing a low sodium chloride concentration (0.1% or less). Although ESW-L has been confirmed to be an effective disinfectant, disinfective efficacy against dried HIV-1 and a target of ESW-L against HIV-1 have not been clarified. In this study, we attempted to demonstrate the efficacy of ESW-L against dried HIV-1 which relatively resists disinfection and to analyze disinfection target. We demonstrated that ESWL inactivated the infectivity of dried HIV-1. In the analysis of the mechanism of disinfection, although the HIV-1 structural protein, p24 within the virus particle, was not inactivated by ESW-L, the enzymatic activity of reverse transcriptase (RT) and genomic RNA within the particle, however, were inactivated after the treatment with ESW-L. These findings suggest that the enzymatic activity of RT and genomic RNA are the target of ESW-L.
Study details
- Published in: Bulletin of Osaka Medical College 48 (2003): 29-36
- Microbes studied: Viruses, HIV
Source
Source: Bulletin of Osaka Medical College 48 (2003): 29-36
Conditions tested
| Parameter | Value |
|---|---|
| Organisms | HIV, Viruses (general) |
| Relevant sectors | Contact surfaces |
| Publication | Bulletin of Osaka Medical College, 2003 |
Reading this responsibly
Published figures are obtained under controlled conditions, usually on clean surfaces or in defined matrices. Organic load, surface condition, temperature and application coverage all affect real-world performance. Use these numbers to design a protocol, then validate it on your own site with environmental swabbing.
Applying it
Concentrations in this range are within the adjustable output of every EcoloxTech commercial system, so implementing this protocol is a settings question rather than a procurement one. Where the claim needs to sit on a registered label, see HOCl-AS200, EPA Reg. No. 101112-1.